Is L-theanine An Effective Anxiety Treatment? (2024)

Is L-theanine An Effective Anxiety Treatment? (1)

L-theanine may sound like an unknown substance, but there’s a good chance you have encountered it before: for example, in the cup of green tea you drank this morning. Questions have been raised about whether L-theanine, a type of amino acid, can have beneficial effects for those suffering from anxiety.

In this article, we'll explore some of the potential benefits and drawbacks of taking L-theanine for your anxiety.

How Does L-Theanine Work?

Because they have access to the central nervous system, psychoactive substances such as L-theanine are believed to have the ability to affect mental abilities and states including your perception of the outer world, the speed at which you think, and the mood you are in.

It is thought to have a stronger effect when combined with caffeine (the world’s most widely consumed psychoactive substance), which is also naturally found in green tea.

Possible Benefits of L-Theanine for Anxiety

Most of L-theanine’s effects have to do with promoting relaxation and positively affecting mood, though not all these effects have been shown to be consistent, and some have the potential to cause drug-seeking behavior when used excessively. L-theanine use triggers the following potentially positive responses in the brain for users with anxiety issues:

  • Affects Alpha Waves in the Brain Alpha waves are the brain waves associated with the state of waking relaxation. They reach their highest levels when a person is awake, relaxed, and has their eyes shut, but disappear when drowsiness or sleep commences. L-theanine has been shown to stimulate the brain’s alpha waves, suggesting that it can put users into a more relaxed state without ultimately causing them to fall asleep.
  • Increases Dopamine Levels Dopamine, the neurotransmitter that is released by the brain as a “reward” after engaging in “rewarding” activities such as consuming food or having sex, increases in the brain in response to L-theanine. Substances that cause the release of high levels dopamine can be addictive, resulting in a compulsion to seek the perceived feeling of “reward.” However, L-theanine produces low enough levels of dopamine that has not been shown to produce “seeking” or addicted behavior in lab tests on rats or in the (more limited) tests on human subjects.
  • Increases GABA (Gamma-Amino-Butyric Acid) levels GABA is an acid whose function is to inhibit or limit neuron activity in the brain. This has the effect of slowing neural processes and inducing a state of relaxation. There is some belief that L-theanine increases GABA levels.
  • Can Increase Serotonin Levels L-theanine does not consistently increase the brain’s serotonin “happy” neurotransmitter, associated with positive mood enhancement, but has been shown to result in an increase in some instances. Mood enhancement may limit anxiety by promoting positive thinking and discouraging obsessive negative thoughts.
  • (+ Caffeine) Improves Memory and Reaction Time When combined with caffeine, L-theanine has been shown to promote faster reaction time and improve memory through the interaction of calming mood improvement effects of L-theanine and the stimulant effects of caffeine. When anxiety makes it difficult to concentrate, or to remember names or essential facts (which can cause further anxiety later on), the combination of these two psychoactive substances can penetrate the brain and aid focus and information retention.

If you are a person who experiences anxiety that interferes with your functionality on a regular basis, the above effects may help to put you in a better frame of mind. However, it is good to remember that similar effects can be achieved through other means, as L-theanine use does entail some potential drawbacks. Both the drawbacks of L-theanine and alternative methods of achieving the above effects are outlined below.

Possible Drawbacks of L-Theanine for Anxiety

If you choose to use L-theanine as a treatment for anxiety, you should make sure that you are informed of its potential drawbacks, which depend largely on how the supplement is used. Knowing how to limit any adverse side effects and understanding why they may help to prevent any unnecessary stress when using this supplement.

  • Can Decrease Serotonin Levels While L-theanine also has the potential to increase serotonin levels in the brain, it has occasionally been shown to decrease them as well. A decrease of serotonin in the brain may result in an increase in stress and tension, which is the opposite of the desired effect for anxiety sufferers. Fortunately, the other positive effects L-theanine triggers in the brain may help to mitigate the adverse consequences of this possible effect.
  • (+ Caffeine) Mental Stimulant When L-theanine is ingested in the form of green tea (a substance that also naturally contains caffeine) or in combination with another caffeinated beverage or supplement, the side effects of the caffeine for a person with anxiety must also be taken into consideration. Caffeine stimulates the brain and increases the heart rate, which in turn increase the likelihood of strong reactions to anxiety-producing stimuli. L-theanine can temper this effect, but if caffeine is used to supplement L-theanine it should be used in small quantities. “Decaffeinated” green tea, for example, contains low levels of caffeine and may be a better choice than regular, fully caffeinated green tea.

Does L-Theanine Work?

As is usually the case with nutritional supplements and their effect on anxiety, there is very little evidence that L-Theanine is an effective treatment. Serious side-effects have not been documented, but there are also almost no studies that confirm that this supplement can affect your overall mood. When using these types of supplements, it's a good idea to talk to a doctor first and make sure that you never depend on it alone. Always make sure that you combine any supplement or medicine with lifestyle changes and techniques that do not require any supplementation, both to decrease the need for the supplement and to make sure that even if the supplement doesn't work, you're still reducing your anxiety.

Alternative Methods for Achieving L-Theanine Benefits

L-theanine benefits such as increasing serotonin levels and resulting in alpha-wave production in the brain can also be achieved through positive lifestyle choices that are free to make and can have additional anti-stress benefits. To find out what you can do to produce some of the benefits of L-theanine without using L-theanine itself, see the list below.

  • Go for a Run To get inside your brain and trigger “happy” chemicals without the help of blood-brain barrier crossing psychoactive substances, all you have to do is grab a pair of running shoes and get your body moving. When you exercise, your brain naturally produces the “happy” chemical serotonin, which helps to ease any stress or discomfort your body undergoes while it is working its muscles during exercise. Running, unlike taking supplements, also improves your body’s overall health—the health of the heart and lungs in particular. A healthy body with healthy organs is naturally less stressed out than an unhealthy one because it doesn’t have to work as hard to function.
  • Practice Meditation Meditating is a great way to relax both your body and your mind, as well as promoting those calming alpha brain waves, while also training your brain to enter a relaxed state through will alone— something that supplements can’t help you to do. Relying on a daily meditation session to relax you first thing in the morning or just before you go to sleep is both less expensive and more beneficial for your anxiety than relying on supplements, which you have to buy regularly and only work in the short term.
  • Join a Sports Team Team sports, like running, get your body moving and cause it to produce the “happy” chemical serotonin. They also usually involve casual social contact with others, which has been scientifically linked to improved mood and decreased stress in humans. Having teammates to talk with and relate to can also help to improve mood, as well as providing a distraction from your worries. When you have no distractions from your anxiety, small concerns have the opportunity to grow, resulting in further anxiety.

Decreasing anxiety by taking L-theanine as a supplement, either in the form of capsules or a mug of decaffeinated green tea, appears to be a low-risk way to address your anxiety issues. On the other hand, many of the positive effects of L-theanine plus additional benefits can be achieved through engaging in the lifestyle choices listed above.

Combining L-Theanine with Lifestyle Changes

Exercising while using L-theanine supplemented by caffeine should be avoided, especially if you are experiencing any heart or blood pressure problems. If you are using L-theanine in a caffeinated form but also exercise regularly, it is advisable to wait at least four hours after ingesting a caffeinated substance before exercising.

L-theanine supplemented by small doses of caffeine, such as the levels that can be found in “decaf” green tea, may be beneficial in combination with meditation. Meditation is an practice associated with slowing your heart rate rather than speeding it up, which means that low levels of caffeine don’t interact negatively with it. Also, the ability of L-theanine combined with caffeine to increase focus and improve memory may help to develop your mind’s ability to enter a meditative, relaxed state more easily.

No matter what you decide, however, never take L-theanine or any supplement alone. Studies have shown time and time again that there are non-pharmacological means to managing anxiety, and while theanine may be natural, it is still considered to be a medicine.

Is L-theanine An Effective Anxiety Treatment? (2024)

FAQs

Is L-theanine An Effective Anxiety Treatment? ›

As is usually the case with nutritional supplements and their effect on anxiety, there is very little evidence that L-Theanine is an effective treatment. Serious side-effects have not been documented, but there are also almost no studies that confirm that this supplement can affect your overall mood.

Is L-theanine proven to help anxiety? ›

L-theanine is a compound known for its calming effect on the mind. In studies, it significantly reduced stress levels, making it a popular option today for people seeking natural remedies for anxiety. One of the ways L-theanine is thought to help reduce anxiety is by increasing levels of certain chemicals in the brain.

Does L-theanine actually work? ›

They noted that it seems to have neuroprotective effects, which improve brain function. On its own, L-theanine may improve a person's attention and reaction times. In combination with caffeine, it may lead to improvements in their number skills and alertness.

What happens if you take L-theanine every day? ›

When taken by mouth: L-theanine is possibly safe when used short-term. Doses of up to 900 mg daily have been safely used for 8 weeks. It isn't clear if L-theanine is safe to use for longer periods of time. It might cause mild side effects, such as headache or sleepiness.

What are the negative side effects of L-theanine? ›

High doses on daily basis will lead to:
  • Lowering blood pressure (which may be beneficial to some people).
  • Appetite loss.
  • Diarrhea.>
  • Difficulty in concentration.
  • Headache.
  • Nausea.
  • Extreme high doses (29mg/kg/day) can cause liver toxicity.

Is ashwagandha or L-theanine better for stress? ›

While L-theanine helps you relax when you need to give yourself a time out, ashwagandha helps you keep from getting all worked up in the first place! Indeed, ashwagandha is practically the poster child of adaptogens (substances that help support healthy stress response and cortisol levels).

Does magnesium really help with anxiety? ›

The good news is that some studies (study links, a and b) have identified how magnesium may ease certain symptoms of stress and anxiety. Here are the facts: Magnesium may help to control the chemical messengers (neurotransmitters) in the brain, resulting in a calming effect on the body.

Is L-theanine hard on the liver? ›

Thus, L-theanine attenuates the inflammatory response caused by ethanol metabolism and reduces the ensuing liver damage. There are several preliminary studies on liver inflammation protection of theanine.

How much L-theanine per day for anxiety? ›

L-theanine Dosage for Anxiety

The supplement is made from extracts. This is because it would require large amounts of naturally occurring sources to get the same results since the amino acids are naturally low in tea leaves. The recommended daily intake of l-theanine for anxiety is about 200 to 400 mg daily.

How long does it take for L-theanine to kick in? ›

However, the original claims relating to the calming effect of l-theanine show it is usually noted within 40–60 min after l-theanine ingestion at a dose of 50–200 mg. Effective dose of 200 mg of l-theanine in the present study to induce relaxation is well consistent with the work of Kobayashi et al.

What not to mix with L-theanine? ›

Medications for high blood pressure (Antihypertensive drugs)Interaction Rating: Moderate Be cautious with this combination. Talk with your health provider. Theanine might decrease blood pressure. Taking theanine along with medications for high blood pressure might cause your blood pressure to go too low.

Does L-theanine affect heart? ›

Researchers in one study found that doses of 250 mg and 400 mg of L-theanine greatly improved sleep in animals and humans (16). Also, 200 mg of L-theanine was shown to help reduce resting heart rate, pointing to its ability to promote relaxation (16).

Does L-theanine make you happier? ›

The connection between l-theanine and happiness

They're so important that they're often referred to as "the building blocks of life." "A growing body of research suggests that l-theanine helps promote healthy moods," Dr. Amen says.

What time of day should I take L-theanine for anxiety? ›

L-theanine can be taken at any time of day, including in the morning to help support healthy stress response and at night before bed to promote restful sleep.

What are the benefits of theanine for anxiety? ›

Like other B-complex vitamins, thiamine is sometimes called an "anti-stress" vitamin because it may strengthen the immune system and improve the body's ability to withstand stressful conditions.

Can I take L-theanine and magnesium together? ›

For most people, it should be safe to combine L-theanine and magnesium, as both are safe at reasonable doses. The pair aren't well studied together, but research does not indicate that taking them together would be a problem.

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